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PMID: 6638992 Published · ppublish English Journal Article

In vitro activities of new beta-lactam antibiotics against Acinetobacter spp.

Antimicrobial agents and chemotherapy ·Vol. 24 ·No. 2 ·1983-08-00 ·Pages 297-9

Garcia I, Fainstein V, LeBlanc B, Bodey GP

Abstract

The in vitro activities of new beta-lactam antibiotics was studied and compared with those of other known agents against 51 clinical isolates of Acinetobacter calcoaceticus subsp. anitratus and 23 isolates of A. calcoaceticus subsp. lwoffi. Of the new beta-lactam antibiotics, imipemide (N-formimidoyl thienamycin), ceftazidime, ceftizoxime, ceftriaxone, and piperacillin demonstrated good activities. The minimal inhibitory concentrations for A. calcoaceticus subsp. lwoffi were lower than those obtained for A. calcoaceticus subsp. anitratus.

MeSH Terms
Acinetobacter/drug effects Anti-Bacterial Agents/pharmacology Microbial Sensitivity Tests beta-Lactams
Chemicals
Anti-Bacterial Agents beta-Lactams
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Garcia I
Fainstein V
LeBlanc B
Bodey G P
References (8)
8 references, click to expand
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    Ann Intern Med. 1982 Nov;97(5):755-60 PMID: 6215872
  2. A comparison of the antibacterial activities of N-formimidoyl thienamycin (MK0787) with those of other recently developed beta-lactam derivatives.
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    Ann Intern Med. 1982 Sep;97(3):408-19 PMID: 6810737
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    Antimicrob Agents Chemother. 1981 Aug;20(2):226-30 PMID: 7283419
  7. Comparative in vitro study of temocillin (BRL 17421), a new penicillin.
    Antimicrob Agents Chemother. 1982 Apr;21(4):641-5 PMID: 6919412
  8. Infections with Acinetobacter calcoaceticus (Herellea vaginicola): clinical and laboratory studies.
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Article Info
Journal
Antimicrobial agents and chemotherapy
Abbr.
Antimicrob Agents Chemother
ISSN
0066-4804
Published
1983-08-00
Pages
297-9
Language
English
Region
United States
NLM ID
0315061
PMCID
PMC185157
Subset
IM
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