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PMID: 6693914 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

The olfactory bulbs in Alzheimer's disease.

Journal of neurology, neurosurgery, and psychiatry ·Vol. 47 ·No. 1 ·1984-01-00 ·Pages 56-60

Esiri MM, Wilcock GK

Abstract

The olfactory bulbs have been examined in patients with Alzheimer's disease and compared with those in elderly undemented and younger undemented control patients. In Alzheimer's disease neurofibrillary tangles were found in the anterior olfactory nucleus but not elsewhere in the olfactory bulb. Cell loss in the anterior olfactory nucleus was also found in Alzheimer's disease. It is clear that the olfactory sensory pathway is pathologically affected in Alzheimer's disease and would merit further study.

MeSH Terms
Alzheimer Disease/pathology Frontal Lobe/pathology Humans Middle Aged Neurofibrils/ultrastructure Neurons/ultrastructure Olfactory Bulb/pathology Temporal Lobe/pathology
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Esiri M M
Wilcock G K
References (11)
11 references, click to expand
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Article Info
Journal
Journal of neurology, neurosurgery, and psychiatry
Abbr.
J Neurol Neurosurg Psychiatry
ISSN
0022-3050
DOI
10.1136/jnnp.47.1.56
Published
1984-01-00
Pages
56-60
Language
English
Region
England
NLM ID
2985191R
PMCID
PMC1027641
Subset
IM
External Links
PubMed source DOI: 10.1136/jnnp.47.1.56 PMC Full Text View journal details
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