[Distribution of myosin in a primary culture of human aortic intimal cells].

Using antiserum against smooth muscle myosin of human uterus the distribution of myosin was investigated in primary cell culture of human aortic intima. It was discovered that during the first 5 days of cultivation, 74.5% of cells manifested homogenous distribution of myosin. Single cells contained myosin in the form of continuous fibrils and 25% of cells were not stained by antiserum. In the next days of cultivation the cells experienced modulation and on the 14th day less than 6% of cells were stained homogeneously, while 58.5% of cells were not stained by antiserum. It is assumed that part of human aortic intima cells might be phenotypically modulated.