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PMID: 6752286 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Development of a bioassay for anti tumor activity of biological response modifiers of the reticuloendothelial stimulant class: reproducibility of the bioassay.

Journal of immunopharmacology ·Vol. 3 ·No. 3-4 ·1981-00-00 ·Pages 385-95

Proctor JW, Yamamura Y, DiLuzio NR, Mansell PW

Abstract

Intravenously administered DiLuzio glucan, Wellcome C. parvum, and Glaxo BCG caused dose dependent increases in the tumor cell loss from the lungs of C57BL/6J and DBA/2J mice challenged respectively with intravenous 125IuDR labelled B16 or T 1699 mammary carcinoma cells. The results were reproducible with respect to the optimal doses and the magnitudes and shapes of the dose response curves.

MeSH Terms

Adjuvants, Immunologic/pharmacology Animals Biological Products/pharmacology Dose-Response Relationship, Immunologic Female Glucans/pharmacology Immunologic Techniques Male Mammary Neoplasms, Experimental/immunology Melanoma/immunology Mice Mice, Inbred C57BL Mice, Inbred DBA Mononuclear Phagocyte System/immunology Mycobacterium bovis/immunology Neoplasms, Experimental/immunology Propionibacterium acnes/immunology

Chemicals

Adjuvants, Immunologic Biological Products Glucans

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Proctor J W

Yamamura Y

DiLuzio N R

Mansell P W

Article Info

Journal

Journal of immunopharmacology

Abbr.

J Immunopharmacol

ISSN

0163-0571

DOI

10.3109/08923978109031069

Published

1981-00-00

Pages

385-95

Language

English

Region

United States

NLM ID

7901853

Subset

Grants

NCI NIH HHS · CA 24936 · United States

NCRR NIH HHS · S 207 RR05801-03 · United States

External Links

PubMed source DOI: 10.3109/08923978109031069

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Development of a bioassay for anti tumor activity of biological response modifiers of the reticuloendothelial stimulant class: reproducibility of the bioassay.

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