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PMID: 6767809 Published · ppublish English Comparative Study Journal Article Research Support, U.S. Gov't, P.H.S.

Cellular differences in the molecular mechanisms of vaccinia virus host range restriction.

The Journal of general virology ·Vol. 47 ·No. 2 ·1980-04-00 ·Pages 485-8

Hruby DE, Lynn DL, Condit RC, Kates JR

Abstract

The biochemistry of vaccinia virus replication in two permissive (BSC-40, L-929), and two non-permissive (CHO, MDBK) cell lines has been compared. While CHO and MDBK cells differentially allowed expression of the various stages in the vaccinia developmental programme, neither cell supported production of any infectious progeny virions.

MeSH Terms
Animals Cattle Cell Line Cricetinae DNA, Viral/biosynthesis Female Haplorhini Kidney L Cells Mice Ovary Vaccinia virus/growth & development,metabolism Viral Proteins/biosynthesis Virus Cultivation
Chemicals
DNA, Viral Viral Proteins
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Hruby D E
Lynn D L
Condit R C
Kates J R
Article Info
Journal
The Journal of general virology
Abbr.
J Gen Virol
ISSN
0022-1317
DOI
10.1099/0022-1317-47-2-485
Published
1980-04-00
Pages
485-8
Language
English
Region
England
NLM ID
0077340
Subset
IM
External Links
PubMed source DOI: 10.1099/0022-1317-47-2-485 View journal details
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