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PMID: 6785912 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Ly-15: a new murine lymphocyte alloantigenic locus.

Transplantation ·Vol. 31 ·No. 5 ·1981-05-00 ·Pages 339-42

Potter TA, Hogarth PM, McKenzie IF

Abstract

Immunization between CXB recombinant inbred mice selected for their identity at known loci led to the production of antisera recognizing two specificities: the previously described Ly-9.2 alloantigen and a new specificity, Ly-15.1. A monoclonal antibody to the Ly-15.2 specificity is also described. The Ly-15 specificities were found on thymus, on lymph node and spleen cells, and on liver, but were absent from kidney, brain, and red blood cells.

MeSH Terms
Animals Antibodies Antibodies, Monoclonal Chromosome Mapping Cytotoxicity, Immunologic Immune Sera/pharmacology Isoantigens/genetics Liver/immunology Lymphocytes/immunology Mice Mice, Inbred AKR Mice, Inbred BALB C Mice, Inbred C3H Mice, Inbred C57BL Mice, Inbred NZB Mice, Inbred Strains Recombination, Genetic Rosette Formation
Chemicals
Antibodies Antibodies, Monoclonal Immune Sera Isoantigens
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Potter T A
Hogarth P M
McKenzie I F
Article Info
Journal
Transplantation
Abbr.
Transplantation
ISSN
0041-1337
Published
1981-05-00
Pages
339-42
Language
English
Region
United States
NLM ID
0132144
Subset
IM
Grants
NCI NIH HHS · CA-22080 · United States
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