Matrix program to analyze primary structure homology.
A FORTRAN program to analyze homology of letter strings (nucleotide or amino acid sequences) and to display the result in the form of a dot matrix is presented. The program is generally usable, user-friendly and has a number of options (filtering, "fudging," i.e., consideration of groups of homologous residues, and screening, i.e., display of only particular groups of residues) which greatly potentiate its analytical power.
6 references, click to expand
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Sequence data handling by computer.Nucleic Acids Res. 1977 Nov;4(11):4037-51 PMID: 593900
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Cloned human and mouse kappa immunoglobulin constant and J region genes conserve homology in functional segments.Cell. 1980 Nov;22(1 Pt 1):197-207 PMID: 6775818
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Structure of the constant and 3' untranslated regions of the murine Balb/c gamma 2a heavy chain messenger RNA.Nucleic Acids Res. 1980 Jul 25;8(14):3143-55 PMID: 6777755
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Three cDNA clones encoding mouse transplantation antigens: homology to immunoglobulin genes.Cell. 1981 Apr;24(1):125-34 PMID: 6786753
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Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a gamma 2a variable region.Cell. 1981 Jun;24(3):625-37 PMID: 6788376
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