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PMID: 6814531 Published · ppublish English Journal Article

A brief consideration of the SOS inducing signal.

Biochimie ·Vol. 64 ·No. 8-9 ·1982-00-00 ·Pages 805-7

Roberts JW, Phizicky EM, Burbee DG, Roberts CW, Moreau PL

Abstract

SOS functions are induced in E. coli by treatments that damage cellular DNA or interrupt its synthesis. The biochemical basis of induction is activation of the specific proteolytic activity of recA protein, which then inactivates the lexA repressor. We discuss the development of the inducing signal in the cell.

MeSH Terms
Bacterial Proteins/genetics Carrier Proteins/genetics DNA Repair DNA Replication Escherichia coli/genetics Mutation Rec A Recombinases Repressor Proteins/genetics Serine Endopeptidases
Chemicals
Bacterial Proteins Carrier Proteins LexA protein, Bacteria Repressor Proteins Rec A Recombinases Serine Endopeptidases
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Roberts J W
Phizicky E M
Burbee D G
Roberts C W
Moreau P L
Article Info
Journal
Biochimie
Abbr.
Biochimie
ISSN
0300-9084
DOI
10.1016/s0300-9084(82)80133-8
Published
1982-00-00
Pages
805-7
Language
English
Region
France
NLM ID
1264604
Subset
IM
External Links
PubMed source DOI: 10.1016/s0300-9084(82)80133-8 View journal details
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