[Demonstration of maturation promoting factor activity in Saccharomyces cerevisiae].

Mise en évidence d'une activité "MPF" chez Saccharomyces cerevisiae.

Comptes rendus des seances de l'Academie des sciences. Serie III, Sciences de la vie ·Vol. 295 ·No. 13 ·1982-12-20 ·Pages 787-90

Weintraub H, Buscaglia M, Ferrez M, Weiller S, Boulet A, Fabre F, Baulieu EE

Abstract

Microinjection of a crude yeast extract into fully grown immature Xenopus laevis oocytes induces the reinitiation of meiotic maturation as does Xenopus laevis oocyte MPF (Maturation Promoting Factor) by itself. Using several strains of yeast exhibiting temperature sensitive cell cycle block (cdc), it was observed that yeast extract exhibits MPF activity only when obtained during the time interval from the G2 period to the metaphase. This observation stresses eucaryotic ubiquity of MPF.

MeSH Terms

Animals Cell Cycle/drug effects Female Growth Substances/analysis,pharmacology In Vitro Techniques Maturation-Promoting Factor Mutation Oocytes/drug effects Saccharomyces cerevisiae/analysis Xenopus laevis

Chemicals

Growth Substances Maturation-Promoting Factor

Authors & Affiliations

7 authors, click to expand affiliations / ORCID

Weintraub H

Buscaglia M

Ferrez M

Weiller S

Boulet A

Fabre F

Baulieu E E

Article Info

Journal

Comptes rendus des seances de l'Academie des sciences. Serie III, Sciences de la vie

Abbr.

C R Seances Acad Sci III

ISSN

0249-6313

Published

1982-12-20

Pages

787-90

Language

fre

Region

France

NLM ID

8108553

Subset

External Links

PubMed source

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[Demonstration of maturation promoting factor activity in Saccharomyces cerevisiae].

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