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PMID: 6892617 Published · ppublish fre English Abstract Journal Article

[Phalloidin counteracts the destructive effects of osmic acid and potassium permanganate on F-actin (author's transl)].

La phalloïdine protège la F-actine contre les effets destructeurs de l'acide osmique et du permanganate.

European journal of cell biology ·Vol. 20 ·No. 3 ·1980-02-00 ·Pages 234-9

Gicquaud C, Gruda J, Pollender JM

Abstract

Osmium tetroxide and potassium permanganate destroy F-actin filaments in vitro, and split actin molecules into smaller peptides. It is shown by viscometry, spectrophotometry, electrophoresis and electron microscopy that the destruction of F-actin by these agents is inhibited by phalloidin. Other proteins are unprotected.

MeSH Terms
Actins/analysis Animals Electrophoresis Microscopy, Electron Muscles Oligopeptides/pharmacology Osmium/pharmacology Osmium Tetroxide/pharmacology Phalloidine/pharmacology Potassium Permanganate/pharmacology Protein Conformation/drug effects Protein Denaturation/drug effects Rabbits Spectrophotometry Viscosity
Chemicals
Actins Oligopeptides Potassium Permanganate Phalloidine Osmium Osmium Tetroxide
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Gicquaud C
Gruda J
Pollender J M
Article Info
Journal
European journal of cell biology
Abbr.
Eur J Cell Biol
ISSN
0171-9335
Published
1980-02-00
Pages
234-9
Language
fre
Region
Germany
NLM ID
7906240
Subset
IM
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