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PMID: 6929943 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

A serum protein polymorphism determinant on chromosome 9 of Mus musculus.

Molecular & general genetics : MGG ·Vol. 177 ·No. 4 ·1980-00-00 ·Pages 571-6

Eicher EM, Taylor BA, Leighton SC, Womack JE

Abstract

Genetic polymorphism for a previously undescribed serum protein has been found among inbred strains of Mus musculus. The new serum protein locus, gene symbol Sep-1, has been located on Chromosome 9, gene order Lap-1--Sep-1--Mpi-1--d--Mod-1, by utilizing information obtained from 52 recombinant inbred strains together with standard genetic backcrosses. The strain distribution pattern for this locus, supernatant malic enzyme, and transferrin also on Chromosome 9, are given for 67 inbred strains. Because the genotype of SEP-1 can be determined for individual mice without killing them, Sep-1 is a very useful gene in linkage studies and experimental biology.

MeSH Terms
Animals Blood Protein Electrophoresis Blood Proteins/genetics Chromosome Mapping Crosses, Genetic Female Genes Malate Dehydrogenase/genetics Male Mannose-6-Phosphate Isomerase/genetics Mice Mice, Inbred Strains/genetics Polymorphism, Genetic Recombination, Genetic Transferrin/genetics
Chemicals
Blood Proteins Transferrin Malate Dehydrogenase Mannose-6-Phosphate Isomerase
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Eicher E M
Taylor B A
Leighton S C
Womack J E
References (21)
21 references, click to expand
  1. Genetic variation in plasma prealbumin of the house mouse.
    J Hered. 1975 Jan-Feb;66(1):19-22 PMID: 1141682
  2. INHERITANCE OF A SERUM PRE-ALBUMIN VARIANT IN THE MOUSE.
    Genetics. 1964 Apr;49:629-34 PMID: 14156923
  3. Recombinant-inbred strains. An aid to finding identity, linkage, and function of histocompatibility and other genes.
    Transplantation. 1971 Mar;11(3):325-7 PMID: 5558564
  4. GENETIC CONTROL OF SERUM TRANSFERRIN TYPE IN MICE.
    Proc Natl Acad Sci U S A. 1960 Oct;46(10):1378-84 PMID: 16590761
  5. Polymorphism and linkage for mannosephosphate isomerase in Mus musculus.
    Biochem Genet. 1973 Jan;8(1):47-53 PMID: 4693062
  6. Influence of gene duplication and X-inactivation on mouse mitochondrial malic enzyme activity and electrophoretic patterns.
    Genetics. 1977 Apr;85(4):647-58 PMID: 863237
  7. Biochemical polymorphisms in feral and inbred mice (mus musculus).
    Biochem Genet. 1971 Oct;5(5):457-66 PMID: 5520794
  8. Genetic analysis of susceptibility to isoniazid-induced seizures in mice.
    Genetics. 1976 Jun;83(2):373-7 PMID: 17248721
  9. LINKAGE OF THE MOUSE TRANSFERRIN LOCUS.
    J Hered. 1963 May-Jun;54:127-9 PMID: 14051864
  10. Mitochondrial malate dehydrogenase and malic enzyme: Mendelian inherited electrophoretic variants in the mouse.
    Biochem Genet. 1970 Dec;4(6):707-18 PMID: 5496232
  11. Genetic polymorphism of murine C3 controlled by a single co-dominant locus on chromosome 17.
    J Immunol. 1978 Aug;121(2):491-8 PMID: 681746
  12. Esterase 13, a new mouse esterase locus with recessive expression and its genetic location on chromosome 9.
    Biochem Genet. 1978 Dec;16(11-12):1107-12 PMID: 751643
  13. Genes for immunoglobulin heavy chain and serum prealbumin protein are linked in mouse.
    Nature. 1975 Aug 21;256(5519):644-6 PMID: 807855
  14. Genetic variation of an intestinal leucine arylaminopeptidase (Lap-1) in the mouse and its location on chromosome 9.
    Biochem Genet. 1975 Oct;13(9-10):511-8 PMID: 1203051
  15. Genetic studies of the Fv-1 locus of mice: linkage with Gpd-1 in recombinant inbred lines.
    J Virol. 1977 Jul;23(1):106-9 PMID: 196096
  16. Genetics of susceptibility to plasmacytoma induction. I. BALB/cAnN (C), C57BL/6N (B6), C57BL/Ka (BK), (C times B6)F1, (C times BK)F1, and C times B recombinant-inbred strains.
    J Natl Cancer Inst. 1975 Jun;54(6):1413-7 PMID: 1133851
  17. Genetic analysis of resistance to cadmium-induced testicular damage in mice.
    Proc Soc Exp Biol Med. 1973 Jul;143(3):629-33 PMID: 4719448
  18. Inbreeding and Linkage.
    Genetics. 1931 Jul;16(4):357-74 PMID: 17246626
  19. Linkage of the locus for serum albumin in the house mouse, Mus musculus.
    Biochem Genet. 1975 Oct;13(9-10):551-5 PMID: 1203054
  20. Murine complement component 3: genetic variation and linkage to H-2.
    Proc Natl Acad Sci U S A. 1978 Feb;75(2):963-5 PMID: 273258
  21. ELECTROPHORETIC VARIATION AND SEX DIMORPHISM OF THE MAJOR URINARY PROTEIN COMPLEX IN INBRED MICE: A NEW GENETIC MARKER.
    J Natl Cancer Inst. 1963 Jul;31:91-107 PMID: 14043041
Article Info
Journal
Molecular & general genetics : MGG
Abbr.
Mol Gen Genet
ISSN
0026-8925
DOI
10.1007/BF00272665
Published
1980-00-00
Pages
571-6
Language
English
Region
Germany
NLM ID
0125036
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00272665
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