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PMID: 6933208 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Genetic mapping of the ecotropic virus-inducing locus Akv-2 of the AKR mouse.

The Journal of experimental medicine ·Vol. 152 ·No. 5 ·1980-11-01 ·Pages 1419-23

Kozak CA, Rowe WP

Abstract

A combination of somatic cell hybridization and standard mendelian breeding techniques was used to map the AKR ecotropic virus inducibility locus Akv-2 to the centromeric end of chromosome 16. This assignment of Akv-2 further emphasizes the endogenous ecotropic retroviruses are inserted at multiple sites in mouse chromosomes.

MeSH Terms
Animals Chromosome Mapping Female Genetic Markers Hybrid Cells Leukemia, Experimental/genetics Male Mice Mice, Inbred AKR Virus Activation
Chemicals
Genetic Markers
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Kozak C A
Rowe W P
References (13)
13 references, click to expand
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    Cancer Res. 1973 Dec;33(12):3061-8 PMID: 4357347
  5. Definitive evidence that the murine C-type virus inducing locus Akv-1 is viral genetic material.
    Proc Natl Acad Sci U S A. 1975 Mar;72(3):906-10 PMID: 1055389
  6. Clonal cells lines from a feral mouse embryo which lack host-range restrictions for murine leukemia viruses.
    Virology. 1975 May;65(1):128-34 PMID: 167514
  7. Relationship of infectious murine leukemia virus and virus-related antigens in genetic crosses between AKR and the Fv-1 compatible strain C57L.
    J Exp Med. 1976 Jan 1;143(1):32-46 PMID: 172587
  8. A sequential staining technique for the chromosomal analysis of the interspecific mouse/hamster and mouse/human somatic cell hybrids.
    Exp Cell Res. 1977 Mar 1;105(1):109-17 PMID: 65290
  9. Gene linkage analysis in the mouse by somatic cell hybridization: assignment of adenine phosphoribosyltransferase to chromosome 8 and alpha-galactosidase to the X chromosome.
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  10. A procedure for culture of cells from mouse tail biopsies: brief communication.
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    Virology. 1978 Jun 15;87(2):287-97 PMID: 208276
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    Proc Natl Acad Sci U S A. 1979 Sep;76(9):4554-8 PMID: 228301
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    J Exp Med. 1980 Jul 1;152(1):219-28 PMID: 6249881
Article Info
Journal
The Journal of experimental medicine
Abbr.
J Exp Med
ISSN
0022-1007
DOI
10.1084/jem.152.5.1419
Published
1980-11-01
Pages
1419-23
Language
English
Region
United States
NLM ID
2985109R
PMCID
PMC2185990
Subset
IM
Grants
NCI NIH HHS · N01-CP-33288 · United States
External Links
PubMed source DOI: 10.1084/jem.152.5.1419 PMC Full Text View journal details
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