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PMID: 6939162 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Preliminary evidence of dual-marked lymphocytes in thoracic duct lymph fluid.

Transplantation proceedings ·Vol. 12 ·No. 3 ·1980-09-00 ·Pages 490-2

Cicciarelli JC, Iwaki Y, Terasaki PI, Guidera K, Shirahama S, Billing R, Hermes M, Cardman L, Kano T, Iwatsuki S, Koep L, Weil R, Starzl TE

Abstract

Thoracic duct lymphocytes from patients receiving thoracic duct drainage as a pretransplant therapy were examined for cell surface markers. Patients followed over the drainage time period showed a variable but decreasing percentage of E-rosette-positive cells in the lymph fluid. A substantial percentage of these E-rosette-positive cells also had C3 receptors on their cell surface. Reactions of the whole lymphocytes with a heteroantisera to human B-lymphocyte antigens reflected the increasing proportion of B cells in the samples, but also indicated that a fraction of the T cells have Ia-like antigens on their surface marker characteristics. Significance of these cells with respect to graft survival is discussed.

MeSH Terms
Animals Drainage Histocompatibility Antigens Class II Humans Leukocyte Count Lymph/cytology Rabbits Receptors, Antigen, B-Cell Receptors, Antigen, T-Cell Receptors, Complement Rosette Formation Thoracic Duct/cytology
Chemicals
Histocompatibility Antigens Class II Receptors, Antigen, B-Cell Receptors, Antigen, T-Cell Receptors, Complement
Authors & Affiliations
13 authors, click to expand affiliations / ORCID
Cicciarelli J C
Iwaki Y
Terasaki P I
Guidera K
Shirahama S
Billing R
Hermes M
Cardman L
Kano T
Iwatsuki S
Koep L
Weil R
Starzl T E
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Article Info
Journal
Transplantation proceedings
Abbr.
Transplant Proc
ISSN
0041-1345
Published
1980-09-00
Pages
490-2
Language
English
Region
United States
NLM ID
0243532
PMCID
PMC2903898
Subset
IM
Grants
NIADDK NIH HHS · AM-17260 · United States
NCRR NIH HHS · M01 RR000069 · United States
NIADDK NIH HHS · AM-07772 · United States
NIDDK NIH HHS · R01 DK029961-19 · United States
NCRR NIH HHS · M01 RR000051 · United States
NIADDK NIH HHS · AM-02375 · United States
External Links
PubMed source PMC Full Text View journal details
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