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PMID: 6985281 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Intracameral inoculation of herpes simplex virus type I induces anterior chamber associated immune deviation.

Current eye research ·Vol. 2 ·No. 10 ·1982-00-00 ·Pages 691-7

Whittum JA, Niederkorn JY, McCulley JP, Streilein JW

Abstract

Herpes simplex virus Type 1 (HSV-1) inoculated intracamerally (IC) into the anterior chamber of BALB/c eyes induces anterior chamber associated immune deviation (ACAID) in which T cell-mediated delayed type hypersensitivity (DTH) responses to HSV-1 are impaired while B cell-mediated anti-HSV neutralizing antibody responses are intact or enhanced.

MeSH Terms

Animals Anterior Chamber/immunology Antibodies, Viral/immunology B-Lymphocytes/immunology Female Herpes Simplex/immunology Hypersensitivity, Delayed/immunology Injections Mice Mice, Inbred BALB C T-Lymphocytes/immunology

Chemicals

Antibodies, Viral

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Whittum J A

Niederkorn J Y

McCulley J P

Streilein J W

Article Info

Journal

Current eye research

Abbr.

Curr Eye Res

ISSN

0271-3683

DOI

10.3109/02713688209019998

Published

1982-00-00

Pages

691-7

Language

English

Region

England

NLM ID

8104312

Subset

Grants

NEI NIH HHS · EY03119 · United States

External Links

PubMed source DOI: 10.3109/02713688209019998 View journal details

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Intracameral inoculation of herpes simplex virus type I induces anterior chamber associated immune deviation.

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