Home LiteratureArticle Details
PMID: 6987736 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Silicone rubber substrata: a new wrinkle in the study of cell locomotion.

Science (New York, N.Y.) ·Vol. 208 ·No. 4440 ·1980-04-11 ·Pages 177-9

Harris AK, Wild P, Stopak D

Abstract

When tissue cells are cultured on very thin sheets of cross-linked silicone fluid, the traction forces the cells exert are made visible as elastic distortion and wrinkling of this substratum. Around explants this pattern of wrinkling closely resembles the "center effects" long observed in plasma clots and traditionally attributed to dehydration shrinkage.

MeSH Terms
Animals Cell Movement Cells, Cultured/physiology Chick Embryo Microscopy, Interference Microscopy, Phase-Contrast Silicone Elastomers
Chemicals
Silicone Elastomers
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Harris A K
Wild P
Stopak D
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
0036-8075
DOI
10.1126/science.6987736
Published
1980-04-11
Pages
177-9
Language
English
Region
United States
NLM ID
0404511
Subset
IM
External Links
PubMed source DOI: 10.1126/science.6987736 View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2