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PMID: 6998982 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S.

Association of creatine phosphokinase with the cytoskeleton of cultured mammalian cells.

The Journal of cell biology ·Vol. 86 ·No. 1 ·1980-07-00 ·Pages 1-5

Eckert BS, Koons SJ, Schantz AW, Zobel CR

Abstract

Using an antibody specific for creatine phosphokinase (CPK), we have discovered an association between that enzyme and the cytoskeleton. Immunofluorescence observations show that CPK is associated with intermediate filaments in PTK cells and BALB/3T3 cells. The CPK distribution also follows intermediate filaments when cells are treated with colchicine.

MeSH Terms
Animals Cells, Cultured Colchicine/pharmacology Creatine Kinase/immunology,metabolism Cytoplasm/enzymology Cytoskeleton/enzymology Fluorescent Antibody Technique Mice
Chemicals
Creatine Kinase Colchicine
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Eckert B S
Koons S J
Schantz A W
Zobel C R
References (34)
34 references, click to expand
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Article Info
Journal
The Journal of cell biology
Abbr.
J Cell Biol
ISSN
0021-9525
DOI
10.1083/jcb.86.1.1
Published
1980-07-00
Pages
1-5
Language
English
Region
United States
NLM ID
0375356
PMCID
PMC2110669
Subset
IM
External Links
PubMed source DOI: 10.1083/jcb.86.1.1 PMC Full Text View journal details
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