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PMID: 7007331 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Globomycin sensitivity of Escherichia coli and Salmonella typhimurium: effects of mutations affecting structures of murein lipoprotein.

Journal of bacteriology ·Vol. 145 ·No. 1 ·1981-01-00 ·Pages 657-60

Lai JS, Philbrick WM, Hayashi S, Inukai M, Arai M, Hirota Y, Wu HC

Abstract

The sensitivity of strains of Escherichia coli and Salmonella typhimurium to globomycin is increased in mutants defective in the lipopolysaccharide structure. E. coli mutants altered in the structures or biosynthesis of murein lipoprotein are more resistant to globomycin than the parental strains.

MeSH Terms
Anti-Bacterial Agents Bacterial Proteins/biosynthesis Drug Resistance, Microbial Escherichia coli/drug effects,genetics,metabolism Lipoproteins/biosynthesis Membrane Proteins/biosynthesis Mutation Peptides/pharmacology Protein Precursors/biosynthesis Salmonella typhimurium/drug effects
Chemicals
Anti-Bacterial Agents Bacterial Proteins Lipoproteins Membrane Proteins Peptides Protein Precursors globomycin
Authors & Affiliations
7 authors, click to expand affiliations / ORCID
Lai J S
Philbrick W M
Hayashi S
Inukai M
Arai M
Hirota Y
Wu H C
References (18)
18 references, click to expand
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.145.1.657-660.1981
Published
1981-01-00
Pages
657-60
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC217322
Subset
IM
Grants
NCI NIH HHS · CA 11371 · United States
External Links
PubMed source DOI: 10.1128/jb.145.1.657-660.1981 PMC Full Text View journal details
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