Legionella micdadei (Pittsburgh pneumonia agent): direct fluoresent-antibody examination of infected human lung tissue and characterization of clinical isolates.
Legionella micdadei (Pittsburgh pneumonia agent) was identified by direct fluorescent-antibody (DFA) examination of lung tissue in six of seven persons diagnosed previously as having L. micdadei pneumonia only by histopathology and in four persons who also had positive cultures of the organism. No cross-reactions occurred with monospecific DFA conjugates prepared against Legionella pneumophila serogroups 1 to 6, Legionella bozemanii, Legionella dumoffii, and Legionella gormanii. One person had L. pneumophila serogroup 6 identified by DFA examination of lung tissue and subsequent culture of stored pulmonary secretions. Characterization of the four strains of L. micdadei revealed specific DFA reactions, bacteriological behavior, and cellular fatty acid composition that allow identification of the organism. DFA testing appears to be a sensitive method for identifying L. micdadei prescent in human lung tissue or cultured on artificial media.
16 references, click to expand
-
Cellular fatty acid composition of isolates from Legionnaires disease.J Clin Microbiol. 1977 Aug;6(2):140-3 PMID: 893658
-
Legionella pneumophila serogroup six: isolation from cases of legionellosis, identification by immunofluorescence staining, and immunological response to infection.J Clin Microbiol. 1980 Sep;12(3):395-401 PMID: 7012173
-
Detection of Legionnaires disease bacteria by direct immunofluorescent staining.J Clin Microbiol. 1978 Sep;8(3):329-38 PMID: 359594
-
Four serogroups of Legionnaires' disease bacteria defined by direct immunofluorescence.Ann Intern Med. 1979 Apr;90(4):621-4 PMID: 86313
-
New bacterial agent of pneumonia isolated from renal-transplant recipients.Lancet. 1979 Jul 14;2(8133):58-61 PMID: 87963
-
Atypical Legionella-like organisms: fastidious water-associated bacteria pathogenic for man.Lancet. 1979 Nov 3;2(8149):927-30 PMID: 91024
-
Opportunistic lung infection due to "Pittsburgh Pneumonia Agent".N Engl J Med. 1979 Nov 1;301(18):953-8 PMID: 386116
-
Opportunistic pneumonia: a clinicopathological study of five cases caused by an unidentified acid-fast bacterium.N Engl J Med. 1979 Nov 1;301(18):959-61 PMID: 386117
-
A Legionella-like bacterium related to WIGA in a fatal case of pneumonia.Ann Intern Med. 1979 Nov;91(5):673-6 PMID: 496099
-
A newly identified bacterium phenotypically resembling, but genetically distinct from, Legionella pneumophila: an isolate in a case of pneumonia.Ann Intern Med. 1979 Dec;91(6):831-4 PMID: 391115
-
The rickettsia-like organisms TATLOCK (1943) and HEBA (1959): bacteria phenotypically similar to but genetically distinct from Legionella pneumophila and the WIGA bacterium.Ann Intern Med. 1980 Jan;92(1):45-52 PMID: 6985783
-
Charcoal-yeast extract agar: primary isolation medium for Legionella pneumophila.J Clin Microbiol. 1979 Oct;10(4):437-41 PMID: 393713
-
TATLOCK bacterium (Pittsburgh pneumonia agent) presumptively identified in five cases of pneumonia.Ann Intern Med. 1980 Apr;92(4):510 PMID: 6987930
-
Pittsburgh pneumonia agent: direct isolation from human lung tissue.J Infect Dis. 1980 Jun;141(6):727-32 PMID: 7391615
-
A fifth serogroup of Legionella pneumophila.Ann Intern Med. 1980 Jul;93(1):58-9 PMID: 7396318
-
Primary isolation media for Legionnaires disease bacterium.J Clin Microbiol. 1978 Sep;8(3):320-5 PMID: 29911
Contact
No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong
Qilu Normal University · Genelibs Bioinformatics Lab
750 Shunhua Rd, Jinan
2F, Bldg F, University Science Park
Tel: 0531-88819269
WeChat Official Account
Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.
Business Email
E-mail: [email protected]
Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2
