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PMID: 7018383 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Purification and some properties of a cephalosporinase from Proteus vulgaris.

Antimicrobial agents and chemotherapy ·Vol. 19 ·No. 1 ·1981-01-00 ·Pages 185-7

Matsubara N, Yotsuji A, Kumano K, Inoue M, Mitsuhashi S

Abstract

The purified cephalosporinase from Proteus vulgaris hydrolyzed a variety of cephalosporins, including cefuroxime, at a high level; its activity was inhibited by clavulanic acid.

MeSH Terms

Cephalosporinase/isolation & purification Kinetics Molecular Weight Proteus vulgaris/enzymology beta-Lactamase Inhibitors beta-Lactamases/isolation & purification

Chemicals

beta-Lactamase Inhibitors Cephalosporinase beta-Lactamases

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Matsubara N

Yotsuji A

Kumano K

Inoue M

Mitsuhashi S

References (17)

17 references, click to expand

Drug resistance of enteric bacteria. XIV. Comparison of beta-lactamases in gram-negative rod bacteria resistant to alpha-aminobenzylpenicillin.
Jpn J Microbiol. 1968 Dec;12(4):423-34 PMID: 5304281
The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis.
J Biol Chem. 1969 Aug 25;244(16):4406-12 PMID: 5806584
Variant of penicillinase mediated by an R factor in Escherichia coli.
J Bacteriol. 1970 Nov;104(2):620-9 PMID: 4923065
Characterization of the -lactamase specified by the resistance factor R-1818 in E. coli K12 and other Gram-negative bacteria.
Biochem J. 1971 Jul;123(4):501-5 PMID: 4942447
Biochemical properties of a cephalosporin beta-lactamase from Pseudomonas aeruginosa.
Jpn J Microbiol. 1973 Mar;17(2):141-9 PMID: 4198890
Cefoxitin, a semisynthetic cephamycin antibiotic: resistance to beta-lactamase inactivation.
Antimicrob Agents Chemother. 1974 Jan;5(1):38-48 PMID: 4599124
A spectrophotometric assay of beta-lactamase action on penicillins.
Biochem J. 1974 Jun;139(3):789-90 PMID: 4368359
Beta-lactamase formation and resistance of Proteus morganii to various penicillins and cephalosporins.
Jpn J Microbiol. 1974 Mar;18(2):113-8 PMID: 4497004
A direct spectrophotometric assay and determination of Michaelis constants for the beta-lactamase reaction.
Anal Biochem. 1975 Jan;63(1):17-26 PMID: 803320
Identification of beta-lactamases by analytical isoelectric focusing: correlation with bacterial taxonomy.
J Gen Microbiol. 1976 May;94(1):55-67 PMID: 819625
Purification and properties of beta-lactamase from Proteus morganii.
J Bacteriol. 1977 Sep;131(3):726-34 PMID: 70426
SCE-129, antipseudomonal cephalosporin: in vitro and in vivo antibacterial activities.
Antimicrob Agents Chemother. 1978 Feb;13(2):137-45 PMID: 417670
Cefuroxime, a beta-lactamase-resistant cephalosporin with a broad spectrum of gram-positive and -negative activity.
Antimicrob Agents Chemother. 1978 Apr;13(4):657-64 PMID: 248268
In vitro antibacterial activity of cefoperazone (T-1551), a new semisynthetic cephalosporin.
Antimicrob Agents Chemother. 1979 Dec;16(6):731-5 PMID: 316988
Activity of beta-lactamase produced by Bacteroides fragilis against newly introduced cephalosporins.
Antimicrob Agents Chemother. 1980 Apr;17(4):736-7 PMID: 6967295
Purification and properties of cephalosporinase in Escherichia coli.
Antimicrob Agents Chemother. 1980 Jul;18(1):77-80 PMID: 6998377
Purification and properties of a new beta-lactamase from Pseudomonas cepacia.
Antimicrob Agents Chemother. 1980 Mar;17(3):355-8 PMID: 6968539

Article Info

Journal

Antimicrobial agents and chemotherapy

Abbr.

Antimicrob Agents Chemother

ISSN

0066-4804

DOI

10.1128/AAC.19.1.185

Published

1981-01-00

Pages

185-7

Language

English

Region

United States

NLM ID

0315061

PMCID

PMC181379

Subset

External Links

PubMed source DOI: 10.1128/AAC.19.1.185 PMC Full Text View journal details

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Purification and some properties of a cephalosporinase from Proteus vulgaris.

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