The biological activity of the synthetic polyanion, pyran copolymer (diveema, MVE, 46015) and the heterocyclic bis DEAE fluorenone derivative, tilorone and congeners: clinical and laboratory effects of these agents as modulators of host resistance.

Adjuvants, Immunologic/pharmacology Animals Anti-Inflammatory Agents/pharmacology Anticoagulants/pharmacology Cell Nucleus/drug effects Cytoplasm/drug effects Fluorenes/pharmacology Humans Immunity, Innate/drug effects Interferon Inducers/pharmacology Macrophage Activation/drug effects Neoplasms/drug therapy Nucleic Acids/metabolism Polymers/pharmacology Pyran Copolymer/pharmacology,therapeutic use,toxicity Tilorone/pharmacology,therapeutic use,toxicity

Adjuvants, Immunologic Anti-Inflammatory Agents Anticoagulants Fluorenes Interferon Inducers Nucleic Acids Polymers Pyran Copolymer Tilorone