Cerebellar pathology in schizophrenia--cause or consequence?

Neuroscience and biobehavioral reviews ·Vol. 6 ·No. 1 ·1982-00-00 ·Pages 47-53

Snider SR

Abstract

Atrophy of the cerebellar vermal cortex has been reported to occur in 10% or more of patients with schizophrenia. Data from studies on experimental animals indicate that a functional relationship between the cerebellum and parts of the forebrain involved in emotion exists, and that the cerebellum may influence some types of behavior. Cerebellar abnormality in schizophrenic patients, although of uncertain cause, could contribute to the symptomatology of the disease.

MeSH Terms

Animals Apomorphine/pharmacology Atrophy Behavior, Animal/drug effects Brain Stem/physiopathology Cats Cerebellar Diseases/complications,physiopathology Cerebellum/pathology,physiopathology Dopamine/physiology Haloperidol/pharmacology Humans Hypothalamus/physiopathology Limbic System/physiopathology Locus Coeruleus/physiopathology Motor Activity/drug effects Neural Pathways Rats Schizophrenia/complications,pathology,physiopathology

Chemicals

Haloperidol Apomorphine Dopamine

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Snider S R

Article Info

Journal

Neuroscience and biobehavioral reviews

Abbr.

Neurosci Biobehav Rev

ISSN

0149-7634

DOI

10.1016/0149-7634(82)90006-9

Published

1982-00-00

Pages

47-53

Language

English

Region

United States

NLM ID

7806090

Subset

External Links

PubMed source DOI: 10.1016/0149-7634(82)90006-9 View journal details

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