Home LiteratureArticle Details

PMID: 7053082 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Structure of an amniotic fluid component, 7-(4,5-cis-dihydroxy-1-cyclopenten-3-ylaminomethyl)-7-deazaguanine (queuine), a substrate for tRNA: guanine transglycosylase.

The Journal of biological chemistry ·Vol. 255 ·No. 18 ·1980-09-25 ·Pages 8405-7

Crain PF, Sethi SK, Katze JR, McCloskey JA

Abstract

A compound present in bovine amniotic fluid, and which is a substrate for tRNA:guanine transglycosylase, has been structurally characterized as queuine, a hypermodified base which occurs in transfer RNA. The structure assignment is based on mass spectrometry, proton nuclear magnetic resonance, and ultraviolet absorbance data.

MeSH Terms

Amniotic Fluid/analysis Animals Biological Assay Cattle Female Guanine/analogs & derivatives,metabolism Magnetic Resonance Spectroscopy Mass Spectrometry Pentosyltransferases Pregnancy Spectrophotometry, Ultraviolet Transferases/metabolism

Chemicals

Guanine queuine Transferases Pentosyltransferases queuine tRNA-ribosyltransferase

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Crain P F

Sethi S K

Katze J R

McCloskey J A

Article Info

Journal

The Journal of biological chemistry

Abbr.

J Biol Chem

ISSN

0021-9258

Published

1980-09-25

Pages

8405-7

Language

English

Region

United States

NLM ID

2985121R

Subset

Grants

NCI NIH HHS · CA 18024 · United States

NCI NIH HHS · CA 202919 · United States

External Links

PubMed source View journal details

Analysis Services

Structure of an amniotic fluid component, 7-(4,5-cis-dihydroxy-1-cyclopenten-3-ylaminomethyl)-7-deazaguanine (queuine), a substrate for tRNA: guanine transglycosylase.

Contact

WeChat Official Account