The true hydrophobicity of microsomal cytochrome P-450 in the rat. Size dependence of the free energy of binding of a series of hydrocarbon substrates from the aqueous phase to the enzyme and to the membrane as derived from spectral binding data.

Animals Benzene Benzene Derivatives Chemical Phenomena Chemistry Cytochrome P-450 Enzyme System/metabolism Kinetics Male Mathematics Microsomes, Liver/metabolism Protein Binding Rats Rats, Inbred Strains Structure-Activity Relationship Thermodynamics

Benzene Derivatives Cytochrome P-450 Enzyme System Benzene