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PMID: 7107521 Published · ppublish English Journal Article

Chemical modification of everninomicins.

The Journal of antibiotics ·Vol. 35 ·No. 5 ·1982-05-00 ·Pages 561-70

Ganguly AK, Girijavallabhan VM, Miller GH, Sarre OZ

Abstract

Novel antibiotic everninomicin D is chemically transformed into new biologically active derivatives. Reactions of a nitro group attached to a tertiary carbon center have been investigated. Synthesis and reactions of hydroxylaminoeverninomicin D, aminoeverninomicin D and their derivatives have been discussed.

MeSH Terms
Aminoglycosides Animals Anti-Bacterial Agents/chemical synthesis,therapeutic use Bacteria/drug effects Bacterial Infections/drug therapy Chemical Phenomena Chemistry Drug Stability Glycosides/chemical synthesis,pharmacology,therapeutic use Rats
Chemicals
Aminoglycosides Anti-Bacterial Agents Glycosides evernimicin
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Ganguly A K
Girijavallabhan V M
Miller G H
Sarre O Z
Article Info
Journal
The Journal of antibiotics
Abbr.
J Antibiot (Tokyo)
ISSN
0021-8820
DOI
10.7164/antibiotics.35.561
Published
1982-05-00
Pages
561-70
Language
English
Region
Japan
NLM ID
0151115
Subset
IM
External Links
PubMed source DOI: 10.7164/antibiotics.35.561 View journal details
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