Systemic lupus erythematosus in Chinese: the Singapore experience.

Rheumatology international ·Vol. 2 ·No. 4 ·1982-00-00 ·Pages 151-4

Feng PH, Boey ML

Abstract

A clinical survey of idiopathic systemic lupus erythematosus (SLE) was conducted in 183 Chinese patients from 1970-1980. The major initial manifestations were skin and mucous membrane involvement (52%), fever and malaise (48%), arthritis and arthralgia (44%). Renal and neuropsychiatric involvements are described in some detail. Five-year survival was 70% and 10-year survival was 60%. The three major causes of death were renal, neurologic and infective. Factors contributing to this relatively high mortality compared with Western series are discussed.

MeSH Terms

Adolescent Adult Asians Female Humans Lupus Erythematosus, Systemic/complications,epidemiology Male Middle Aged Singapore

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Feng P H

Boey M L

References (18)

18 references, click to expand

Epidemiologic studies on systemic lupus erythematosus. Comparative data for New York City and Jefferson County, Alabama, 1956-1965.
Arthritis Rheum. 1970 Nov-Dec;13(6):802-11 PMID: 5495391
Computer analysis of factors influencing frequency of infection in systemic lupus erythematosus.
Arthritis Rheum. 1978 Jan-Feb;21(1):37-44 PMID: 414759
Systemic lupus erythematosus. A prospective analysis.
Ann Rheum Dis. 1978 Apr;37(2):121-8 PMID: 646463
Systemic lupus erythematosus in the community. Incidence, prevalence, outcome, and first symptoms; the high prevalence in black women.
Arch Intern Med. 1974 Dec;134(6):1027-35 PMID: 4433183
High rate of death caused by systemic lupus erythematosus among U. S. residents of Asian descent.
Arthritis Rheum. 1982 Apr;25(4):414-8 PMID: 7073774
The current status of rheumatology in the Peoples Republic of China.
Arthritis Rheum. 1981 Oct;24(10):1324-5 PMID: 6975633
Determination of prognosis in chronic disease, illustrated by systemic lupus erythematosus.
J Chronic Dis. 1955 Jan;1(1):12-32 PMID: 13233308
Tuberculosis in patients with systemic lupus erythematosus.
Ann Rheum Dis. 1982 Feb;41(1):11-4 PMID: 7065724
Racial differences in serum gamma globulin levels: comparative data for Negroes, Puerto Ricans, and other Caucasians.
J Lab Clin Med. 1965 Nov;66(5):715-20 PMID: 4158577
Duration and death in systemic lupus erythematosus. An analysis of 249 cases.
JAMA. 1974 Mar 25;227(12):1399-402 PMID: 4406022
Mortality in systemic lupus erythematosus: a 10-year review.
Br Med J. 1973 Dec 29;4(5895):772-4 PMID: 4758576
Frequency of systemic lupus erythematosus in different ethnic groups in Hawaii.
Arthritis Rheum. 1979 Apr;22(4):328-33 PMID: 426879
Neuropsychiatric problems in systemic lupus erythematosus.
Br Med J. 1972 Nov 11;4(5836):342-5 PMID: 4344384
Apparent predisposition to systemic lupus erythematosus in Chinese patients in West Malaysia.
Ann Rheum Dis. 1980 Jun;39(3):266-9 PMID: 7416817
Management plan of systemic lupus erythematosus -- a flow chart.
Singapore Med J. 1980 Aug;21(4):634-8 PMID: 7221573
Systemic lupus erythematosus. A review of 110 cases with reference to nephritis, the nervous system, infections, aseptic necrosis and prognosis.
Q J Med. 1977 Jan;46(181):1-32 PMID: 866565
Incidence of infection in systemic lupus erythematosus.
Arthritis Rheum. 1974 Jan-Feb;17(1):1-10 PMID: 4810662
Concurrent systemic lupus erythematosus and salmonellosis.
J Rheumatol. 1981 Jul-Aug;8(4):605-12 PMID: 7299762

Article Info

Journal

Rheumatology international

Abbr.

Rheumatol Int

ISSN

0172-8172

DOI

10.1007/BF00286136

Published

1982-00-00

Pages

151-4

Language

English

Region

Germany

NLM ID

8206885

Subset

External Links

PubMed source DOI: 10.1007/BF00286136 View journal details

Analysis Services

Systemic lupus erythematosus in Chinese: the Singapore experience.

Contact

WeChat Official Account