Pharmacology of a new calcium antagonistic compound, isobutyl methyl 1,4-dihydro-2,6-dimethyl-4(2-nitrophenyl)-3,5-pyridinedicarboxylate (Nisoldipine, Bay k 5552).

Animals Blood Coagulation/drug effects Calcium/antagonists & inhibitors,pharmacology Cats Chemical Phenomena Chemistry Diuresis/drug effects Dogs Female Guinea Pigs Hemodynamics/drug effects Hypertension, Renovascular/drug therapy Male Muscle Contraction/drug effects Muscle, Smooth/drug effects Muscle, Smooth, Vascular/drug effects Myocardial Contraction/drug effects Nifedipine/analogs & derivatives,pharmacology Nisoldipine Norepinephrine/pharmacology Potassium/pharmacology Pyridines/pharmacology Rabbits Rats

Pyridines Nisoldipine Nifedipine Potassium Calcium Norepinephrine