Role of Staphylococcus aureus exfoliatin toxin in staphylococcal infections in mice.

Chemotherapy ·Vol. 27 ·No. 3 ·1981-00-00 ·Pages 224-7

Shibl AM

Abstract

Clindamycin at a concentration of 0.18 microgram/ml reduced growth of Staphylococcus aureus in vitro by 40% but inhibited exfoliatin toxin production by 90%. Mice infected with S. aureus and subsequently treated with clindamycin did not exfoliate but still died.

MeSH Terms

Animals Bacterial Toxins/biosynthesis Clindamycin/pharmacology,therapeutic use Exfoliatins/biosynthesis Mice Staphylococcal Infections/drug therapy,metabolism Staphylococcus aureus/drug effects,growth & development,metabolism

Chemicals

Bacterial Toxins Exfoliatins Clindamycin

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Shibl A M

Article Info

Journal

Chemotherapy

Abbr.

Chemotherapy

ISSN

0009-3157

DOI

10.1159/000237982

Published

1981-00-00

Pages

224-7

Language

English

Region

Switzerland

NLM ID

0144731

Subset

External Links

PubMed source DOI: 10.1159/000237982 View journal details

Analysis Services

Role of Staphylococcus aureus exfoliatin toxin in staphylococcal infections in mice.

Contact

WeChat Official Account