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PMID: 7241090 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Diffusion of calcium ions in retinal rods. A theoretical calculation.

The Journal of general physiology ·Vol. 77 ·No. 4 ·1981-04-00 ·Pages 475-87

McLaughlin S, Brown J

Abstract

The Fick diffusion equation is combined with the Langmuir adsorption isotherm and the relevant equations from the Gouy-Chapman theory of the electrical diffuse double layer to demonstrate that the effective diffusion coefficient of calcium ions, both in the cytoplasm of the rod outer segment and within the aqueous space bounded by the disk membrane, should be reduced by a factor of 10-100 because these ions adsorb to phospholipids present in the disk membrane.

MeSH Terms
Calcium/metabolism Cytoplasm/metabolism Mathematics Photoreceptor Cells/metabolism
Chemicals
Calcium
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
McLaughlin S
Brown J
References (31)
31 references, click to expand
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Article Info
Journal
The Journal of general physiology
Abbr.
J Gen Physiol
ISSN
0022-1295
DOI
10.1085/jgp.77.4.475
Published
1981-04-00
Pages
475-87
Language
English
Region
United States
NLM ID
2985110R
PMCID
PMC2215421
Subset
IM
Grants
NEI NIH HHS · EY01914 · United States
NEI NIH HHS · EY01915 · United States
NIGMS NIH HHS · GM24971 · United States
External Links
PubMed source DOI: 10.1085/jgp.77.4.475 PMC Full Text View journal details
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