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PMID: 7258186 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

A simple method for testing two-locus models of inheritance.

American journal of human genetics ·Vol. 33 ·No. 4 ·1981-07-00 ·Pages 519-30

Greenberg DA

Abstract

A graphic method for testing simple two-locus models of inheritance is developed. The model assumes two alleles at each locus where both loci exhibit dominant, both exhibit recessive, or one locus exhibits dominant and one locus exhibits recessive inheritance. Examples of applying the graphs using published data on three diseases are given.

MeSH Terms
Alleles Celiac Disease/genetics Fingers/abnormalities Gene Frequency Hemochromatosis/genetics Humans Models, Genetic Phenotype Probability
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Greenberg D A
References (14)
14 references, click to expand
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Article Info
Journal
American journal of human genetics
Abbr.
Am J Hum Genet
ISSN
0002-9297
Published
1981-07-00
Pages
519-30
Language
English
Region
United States
NLM ID
0370475
PMCID
PMC1685079
Subset
IM
Grants
NIADDK NIH HHS · AM-17328 · United States
External Links
PubMed source PMC Full Text View journal details
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