Importance of bacterial growth phase in determining minimal bactericidal concentrations of penicillin and methicillin.
The minimal inhibitory concentrations of penicillin against 96 strains of group B streptococci and of methicillin against 10 strains of Staphylococcus aureus were unrelated to the growth phase of test bacteria. However, the minimal bactericidal concentrations were significantly higher in the stationary phase than the logarithmic phase for both organisms (P less than 0.001 and less than 0.05, respectively).
5 references, click to expand
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An experimental analysis of the curative action of penicillin in acute bacterial infections. I. The relationship of bacterial growth rates to the antimicrobial effect of penicillin.J Exp Med. 1956 Apr 1;103(4):487-98 PMID: 13306857
-
Experimental approach to the problem of treatment failure with penicillin. I. Group A streptococcal infection in mice.Am J Med. 1952 Oct;13(4):389-99 PMID: 12985596
-
Infectious diseases 1979--antimicrobial susceptibility tests.J Infect Dis. 1979 Aug;140(2):261-3 PMID: 113470
-
Importance of medium in demonstrating penicillin tolerance by group B streptococci.Antimicrob Agents Chemother. 1979 Aug;16(2):214-6 PMID: 384895
-
Distribution by serological type of group B streptococci isolated from a variety of clinical material over a five-year period (with special reference to neonatal sepsis and meningitis).Infect Immun. 1973 Aug;8(2):228-35 PMID: 4725698
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