Home LiteratureArticle Details
PMID: 7271276 Published · ppublish English Journal Article

Interaction between vancomycin and rifampin against Staphylococcus aureus.

Antimicrobial agents and chemotherapy ·Vol. 19 ·No. 6 ·1981-06-00 ·Pages 1089-91

Watanakunakorn C, Guerriero JC

Abstract

By the time-kill method, vancomycin and rifampin were antagonistic against 43 of 50 strains of Staphylococcus aureus, whether susceptible or resistant to methicillin.

MeSH Terms
Drug Interactions Drug Therapy, Combination Humans Methicillin/pharmacology Microbial Sensitivity Tests Rifampin/pharmacology Staphylococcal Infections/drug therapy Staphylococcus aureus/drug effects Vancomycin/pharmacology
Chemicals
Vancomycin Methicillin Rifampin
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Watanakunakorn C
Guerriero J C
References (8)
8 references, click to expand
  1. Comparison of the antibacterial activity of rifampicin and other antibiotics.
    Am J Med Sci. 1968 Oct;256(4):255-65 PMID: 4387027
  2. Antibiotic sensitivity testing. Report of an international collaborative study.
    Acta Pathol Microbiol Scand B Microbiol Immunol. 1971;217:Suppl 217:1+ PMID: 4325956
  3. Killing of intraleukocytic Staphylococcus aureus by rifampin: in-vitro and in-vivo studies.
    J Infect Dis. 1972 May;125(5):486-90 PMID: 5023643
  4. Staphylococcus aureus endocarditis. Combined therapy with vancomycin and rifampin.
    JAMA. 1978 Oct 27;240(18):1963-5 PMID: 249793
  5. Prognostic factors in Staphylococcus aureus endocarditis and results of therapy with a penicillin and gentamicin.
    Am J Med Sci. 1977 Mar-Apr;273(2):133-9 PMID: 871133
  6. The efficacy of rifampin as adjunctive therapy in selected cases of staphylococcal endocarditis.
    Chest. 1978 Mar;73(3):371-5 PMID: 630934
  7. In vitro activity of rifampin alone and in combination with nafcillin and Vancomycin against pathogenic strains of Staphylococcus aureus.
    Antimicrob Agents Chemother. 1978 May;13(5):759-61 PMID: 666300
  8. Failure of vancomycin treatment in Staphylococcus aureus endocarditis. In vivo and in vitro observations.
    JAMA. 1976 Oct 4;236(14):1604-6 PMID: 989135
Article Info
Journal
Antimicrobial agents and chemotherapy
Abbr.
Antimicrob Agents Chemother
ISSN
0066-4804
DOI
10.1128/AAC.19.6.1089
Published
1981-06-00
Pages
1089-91
Language
English
Region
United States
NLM ID
0315061
PMCID
PMC181616
Subset
IM
External Links
PubMed source DOI: 10.1128/AAC.19.6.1089 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2