Home LiteratureArticle Details
PMID: 7277224 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Localization of specialized noradrenaline receptors at neuromuscular junctions on arterioles of the guinea-pig.

The Journal of physiology ·Vol. 313 ·1981-00-00 ·Pages 343-50

Hirst GD, Neild TO

Abstract

1. Noradrenaline was applied by ionophoresis to various positions on the surface of an arteriole, and any changes in membrane potential of the arteriolar smooth muscle were recorded. 2. At a proportion of positions noradrenaline produced membrane depolarization. 3. The positions where noradrenaline produced these membrane potential changes were restricted to regions close to the sympathetic nerves which innervated the arterioles.

MeSH Terms
Animals Arteries/innervation Arterioles/drug effects,innervation Guinea Pigs In Vitro Techniques Membrane Potentials/drug effects Muscle, Smooth, Vascular/physiology Neuromuscular Junction/drug effects Norepinephrine/pharmacology Receptors, Adrenergic/drug effects Sympathetic Nervous System/physiology
Chemicals
Receptors, Adrenergic Norepinephrine
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Hirst G D
Neild T O
References (10)
10 references, click to expand
  1. Synaptic transmission and its duplication by focally applied acetylcholine in parasympathetic neurons in the heart of the frog.
    Proc R Soc Lond B Biol Sci. 1971 Apr 27;177(1049):509-39 PMID: 4396518
  2. Some properties of the junctional and extrajunctional receptors in the vas deferens of the guinea-pig.
    Agents Actions. 1969 Nov;1(2):13-21 PMID: 4398570
  3. The distribution of acetylcholine sensitivity at the post-synaptic membrane of vertebrate skeletal twitch muscles: iontophoretic mapping in the micron range.
    J Physiol. 1975 Jan;244(3):703-30 PMID: 166160
  4. On the latency and form of the membrane responses of smooth muscle to the iontophoretic application of acetylcholine or carbachol.
    Proc R Soc Lond B Biol Sci. 1976 Aug 27;194(1114):99-119 PMID: 11484
  5. Water-stable fluorophores, produced by reaction with aldehyde solutions, for the histochemical localization of catechol- and indolethylamines.
    Histochemistry. 1977 May 20;52(2):159-70 PMID: 406252
  6. Neuromuscular transmission in arterioles of guinea-pig submucosa.
    J Physiol. 1977 Dec;273(1):263-75 PMID: 202698
  7. An analysis of excitatory junctional potentials recorded from arterioles.
    J Physiol. 1978 Jul;280:87-104 PMID: 690942
  8. Evidence for two populations of excitatory receptors for noradrenaline on arteriolar smooth muscle.
    Nature. 1980 Feb 21;283(5749):767-8 PMID: 6243746
  9. Some properties of spontaneous excitatory junction potentials recorded from arterioles of guinea-pigs.
    J Physiol. 1980 Jun;303:43-60 PMID: 6253622
  10. On the localization of acetylcholine receptors.
    J Physiol. 1955 Apr 28;128(1):157-81 PMID: 14368581
Article Info
Journal
The Journal of physiology
Abbr.
J Physiol
ISSN
0022-3751
DOI
10.1113/jphysiol.1981.sp013669
Published
1981-00-00
Pages
343-50
Language
English
Region
England
NLM ID
0266262
PMCID
PMC1274455
Subset
IM
External Links
PubMed source DOI: 10.1113/jphysiol.1981.sp013669 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2