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PMID: 7288145 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Assignment of retinal dystrophy (rdy) to linkage group IV of the rat.

The Journal of heredity ·Vol. 72 ·No. 4 ·1981-00-00 ·Pages 294-6

LaVail MM

Abstract

The retinal dystrophy gene, rdy, in the rat displays autosomal linkage of 19.0 +/- 1.7 percent with nonagouti, a, and 31.8 +/- 4.1 percent with Svp-1 in linkage group IV. The data are consistent with the linear order rdy--a--Svp-1, but the orientation of this sequence with respect to the centromere is not known. A congenic strain has been developed from some of the testcross animals in which retinal dystrophic and heterozygous control rats of both pink-eyed and black-eyed phenotyped can be distinguished with pigmentation marker genes.

MeSH Terms
Animals Chromosome Mapping Crosses, Genetic Female Genes Genes, Recessive Male Pigmentation Disorders/genetics Rats/genetics Retinal Degeneration/genetics
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
LaVail M M
Article Info
Journal
The Journal of heredity
Abbr.
J Hered
ISSN
0022-1503
Published
1981-00-00
Pages
294-6
Language
English
Region
United States
NLM ID
0375373
Subset
IM
Grants
NEI NIH HHS · EY 01919 · United States
NEI NIH HHS · EY 02162 · United States
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