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PMID: 728870 Published · ppublish English Case Reports Journal Article

True hermaphrodite with multiple gonadal neoplasms: report of a case with cytogenetic study.

Cancer ·Vol. 42 ·No. 6 ·1978-12-00 ·Pages 2726-32

Radharrishnan S, Sivaraman L, Natarajan PS

Abstract

On account of the functioning bigonads, true hermaphrodites show a wide range of morphological anomalies. The patient under discussion had an ovary on one side and an ovotestis on the other side; both of them functioned to some extent to produce a rudimentary uterus, fallopian tubes and a few Woolfian remnants. The additional point of interest in this report was the presence of three gonadal neoplasms-namely Yolk Sac Carcinoma gonadoblastoma and seminoma. While the ovary on one side was replaced by yolk sac carcinoma, the ovotestis was partly destroyed by the other two. The cytogenetic study revealed a hypodiploid number and a mosaic sex chromosomal pattern. The karyotypic abnormalities noticed in the patient are also reviewed.

MeSH Terms
Adult Chromosome Aberrations Disorders of Sex Development/complications,genetics Dysgerminoma/complications,genetics Female Humans Male Mosaicism Neoplasms, Multiple Primary/complications,genetics Ovarian Neoplasms/complications,genetics Testicular Neoplasms/complications,genetics
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Radharrishnan S
Sivaraman L
Natarajan P S
Article Info
Journal
Cancer
Abbr.
Cancer
ISSN
0008-543X
Published
1978-12-00
Pages
2726-32
Language
English
Region
United States
NLM ID
0374236
Subset
IM
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