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PMID: 7288921 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Adenovirus type 5 virions can be assembled in vivo in the absence of detectable polypeptide IX.

Journal of virology ·Vol. 39 ·No. 3 ·1981-09-00 ·Pages 977-80

Colby WW, Shenk T

Abstract

Mutant dl313 is an adenovirus type 5 deletion mutant which lacks 2,307 base pairs, including the 5' portion of the polypeptide IX gene. Mutant virions did not contain detectable levels of this polypeptide. They were substantially more thermolabile than wild-type particles and did not produce hexon nonomers upon pyridine disruption.

MeSH Terms
Adenoviruses, Human/analysis,genetics,growth & development Genes, Viral Hot Temperature Mutation Peptides/analysis,physiology Pyridines/pharmacology Viral Proteins/analysis,physiology
Chemicals
Peptides Pyridines Viral Proteins pyridine
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Colby W W
Shenk T
References (22)
22 references, click to expand
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Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
DOI
10.1128/JVI.39.3.977-980.1981
Published
1981-09-00
Pages
977-80
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC171335
Subset
IM
External Links
PubMed source DOI: 10.1128/JVI.39.3.977-980.1981 PMC Full Text View journal details
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