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PMID: 730364 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Survival and multiplication of Vibrio cholerae in the upper bowel of infant mice.

Infection and immunity ·Vol. 22 ·No. 2 ·1978-11-00 ·Pages 435-40

Baselski VS, Medina RA, Parker CD

Abstract

The survival and multiplication of Vibrio cholerae strains of varying virulence in the upper bowel of orally challenged infant mice early in infection has been examined. Analysis of changes in the apparent specific activity (counts per minute per colony-forming unit) of the cell population after 4 h compared with the inoculum indicated that strain CA401 established a viable, multiplying cell population, whereas strains VB12 (a rough variant) and 569B were subject to host bactericidal and bacteriolytic mechanisms. An analysis of parameters which may affect the specific activity is included. We have defined the infective potential of the strains in terms of the changes in specific activity. The relative infective potentials are CA401 greater than 569B greater than VB12.

MeSH Terms
Animals Cell Division Cholera/microbiology Intestinal Diseases/microbiology Intestine, Small/microbiology Mice Species Specificity Vibrio cholerae/growth & development,pathogenicity
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Baselski V S
Medina R A
Parker C D
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22 references, click to expand
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Article Info
Journal
Infection and immunity
Abbr.
Infect Immun
ISSN
0019-9567
DOI
10.1128/iai.22.2.435-440.1978
Published
1978-11-00
Pages
435-40
Language
English
Region
United States
NLM ID
0246127
PMCID
PMC422175
Subset
IM
External Links
PubMed source DOI: 10.1128/iai.22.2.435-440.1978 PMC Full Text View journal details
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