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PMID: 7306076 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Cytochrome b-245 of neutrophils is also present in human monocytes, macrophages and eosinophils.

The Biochemical journal ·Vol. 196 ·No. 1 ·1981-04-15 ·Pages 363-7

Segal AW, Garcia R, Goldstone H, Cross AR, Jones OT

Abstract

A cytochrome b with a midpoint oxidation-reduction potential of -245mV (cytochrome b-245) that is a major component of the microbicidal oxidase system of human neutrophil leucocytes has been identified in human eosinophils, monocytes and macrophages at concentrations similar to that found in human neutrophils. It was absent from a variety of other cells. This cytochrome is present in phagocytic leucocytes and probably plays an important part in the specialized activities of these cells.

MeSH Terms
Animals Cytochrome b Group Cytochromes/blood Eosinophils/enzymology Humans Macrophages/enzymology Monocytes/enzymology Neutrophils/enzymology Oxidation-Reduction Potentiometry Rats Spectrophotometry
Chemicals
Cytochrome b Group Cytochromes
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Segal A W
Garcia R
Goldstone H
Cross A R
Jones O T
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26 references, click to expand
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Article Info
Journal
The Biochemical journal
Abbr.
Biochem J
ISSN
0264-6021
Published
1981-04-15
Pages
363-7
Language
English
Region
England
NLM ID
2984726R
PMCID
PMC1163001
Subset
IM
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