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PMID: 7325633 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Antimicrobial susceptibility of intracellular Legionella pneumophila.

Antimicrobial agents and chemotherapy ·Vol. 20 ·No. 5 ·1981-11-00 ·Pages 691-2

Bacheson MA, Friedman HM, Benson CE

Abstract

Minimum inhibitory concentrations, minimum bactericidal concentrations, and killing curve assays were measured after Legionella pneumophila was grown in human lung fibroblasts. Results of susceptibility testing of organisms grown intracellularly are compared with results for organisms grown by standard tube dilution methods.

MeSH Terms

Anti-Bacterial Agents/pharmacology Cefamandole/pharmacology Cells, Cultured Erythromycin/pharmacology Fibroblasts Gentamicins/pharmacology Legionella/drug effects Microbial Sensitivity Tests Time Factors

Chemicals

Anti-Bacterial Agents Gentamicins Cefamandole Erythromycin

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Bacheson M A

Friedman H M

Benson C E

References (10)

10 references, click to expand

Legionnaires' disease: description of an epidemic of pneumonia.
N Engl J Med. 1977 Dec 1;297(22):1189-97 PMID: 335244
Demonstration of the agent of Legionnaires' disease in tissue.
N Engl J Med. 1977 Dec 1;297(22):1218-20 PMID: 72358
Antibiotic treatment of guinea-pigs infected with agent of Legionnaires' disease.
Lancet. 1978 Jan 28;1(8057):175-8 PMID: 74604
In vitro susceptibility of Legionella pneumophila, serogroups I-IV.
J Infect Dis. 1979 Aug;140(2):251 PMID: 479642
In vivo susceptibility of the Legionnaires disease bacterium to ten antimicrobial agents.
Antimicrob Agents Chemother. 1978 Mar;13(3):419-22 PMID: 263885
Legionnaires' disease bacterium (Legionella pneumophila) multiples intracellularly in human monocytes.
J Clin Invest. 1980 Sep;66(3):441-50 PMID: 7190579
Legionnaires' disease: report of sixty-five nosocomially acquired cases of review of the literature.
Medicine (Baltimore). 1980 May;59(3):188-205 PMID: 6997673
Susceptibility of Legionella pneumophila to twenty antimicrobial agents.
Antimicrob Agents Chemother. 1980 Sep;18(3):403-8 PMID: 7425611
Intracellular replication of Legionella pneumophila.
J Infect Dis. 1981 Mar;143(3):460-4 PMID: 7014732
Intracellular multiplication of Legionella pneumophila in cultured human embryonic lung fibroblasts.
Infect Immun. 1980 Jun;28(3):1014-8 PMID: 7399685

Article Info

Journal

Antimicrobial agents and chemotherapy

Abbr.

Antimicrob Agents Chemother

ISSN

0066-4804

DOI

10.1128/AAC.20.5.691

Published

1981-11-00

Pages

691-2

Language

English

Region

United States

NLM ID

0315061

PMCID

PMC181776

Subset

Grants

NIAID NIH HHS · AI-15848 · United States

External Links

PubMed source DOI: 10.1128/AAC.20.5.691 PMC Full Text View journal details

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Antimicrobial susceptibility of intracellular Legionella pneumophila.

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