Accelerated conversion of heme to bile pigments caused in the liver by carbon disulfide and other sulfur-containing chemicals.

Animals Bile Pigments/biosynthesis Carbon Disulfide/pharmacology Cycloheximide/pharmacology Cytochrome P-450 Enzyme System/metabolism Heme/metabolism Liver/drug effects,metabolism Male Microsomes, Liver/drug effects,metabolism Mixed Function Oxygenases/metabolism Phenobarbital/pharmacology Rats Sulfur/pharmacology

Bile Pigments Heme Sulfur Cytochrome P-450 Enzyme System Cycloheximide Mixed Function Oxygenases Carbon Disulfide Phenobarbital