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PMID: 7350061 Published · ppublish English Case Reports Journal Article Research Support, U.S. Gov't, P.H.S.

Dyspepsia, antral motor dysfunction, and gastric stasis of solids.

Gastroenterology ·Vol. 78 ·No. 2 ·1980-02-00 ·Pages 360-5

Rees WD, Miller LJ, Malagelada JR

Abstract

Extensive gastric manometric and emptying studies were performed in a patient with postprandial dyspeptic symptoms which, for many years, had been diagnosed as functional complaints. After ingestion of a mixed, solid-liquid meal we observed marked gastric stasis of solids associated with a weak antral pressure response, whereas gastric emptying of fluids was normal. Fundic pressure activity, recorded separately, was also normal. This case may represent a pathophysiologic expression of the specific roles of the antrum in the emptying of solids (abnormal) and of the fundus in the emptying of liquids (normal) and shows that pathophysiologic abnormalities can sometimes be demonstrated in patients lumped under a "functional" category.

MeSH Terms
Aged Bethanechol Compounds/therapeutic use Duodenum/physiopathology Dyspepsia/diagnostic imaging,physiopathology Eating Gastric Emptying/drug effects Gastrointestinal Motility/drug effects Glucagon/therapeutic use Humans Male Manometry Metoclopramide/therapeutic use Pyloric Antrum/physiopathology Radiography
Chemicals
Bethanechol Compounds Glucagon Metoclopramide
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Rees W D
Miller L J
Malagelada J R
Article Info
Journal
Gastroenterology
Abbr.
Gastroenterology
ISSN
0016-5085
Published
1980-02-00
Pages
360-5
Language
English
Region
United States
NLM ID
0374630
Subset
IM
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