Induction of peroxisomal beta-oxidation in rat liver by high-fat diets.
Liver peroxisomes were prepared by using a Percoll gradient in a vertical rotor. beta-Oxidation was measured in peroxisomes isolated from livers of rats fed on either high-(15% by wt.) or low- (5% by wt.) fat diets. The feeding of high-fat diets gave a 1.4-2.4-fold increase in total liver peroxisomal beta-oxidation, and a similar increase in specific activity. A 1.5-4.5-fold increase was seen in the specific activity of purified peroxisomal preparations. The reasons for these increases are discussed.
9 references, click to expand
-
Increase of hepatic mitochondria on administration of ethyl alpha-p-chlorophenoxyisobutyrate to the rat.Biochem J. 1970 Mar;116(5):773-9 PMID: 5441366
-
Studies on monoene fatty acid isomers in hydrogenated fish oils.J Am Oil Chem Soc. 1971 Aug;48(8):389-91 PMID: 5167041
-
A fatty acyl-CoA oxidizing system in rat liver peroxisomes; enhancement by clofibrate, a hypolipidemic drug.Proc Natl Acad Sci U S A. 1976 Jun;73(6):2043-6 PMID: 180535
-
Distribution of organelles and membranes between hepatocytes and nonhepatocytes in the rat liver parenchyma. A stereological study.J Cell Biol. 1977 Feb;72(2):441-55 PMID: 833203
-
Enhancement of fatty acyl-CoA oxidizing activity in rat liver peroxisomes by di-(i-ethylhexyl)phthalate.J Biochem. 1978 May;83(5):1361-5 PMID: 659402
-
Effect of marine oil and rapeseed oil on composition of fatty acids in lipoprotein triacylglycerols from rat blood plasma and liver perfusate.Lipids. 1979 Jan;14(1):58-65 PMID: 423712
-
Peroxisomal oxidation of long chain fatty acids.FEBS Lett. 1979 Mar 15;99(2):292-6 PMID: 34532
-
The stimulation of erucate metabolism in isolated rat hepatocytes by rapeseed oil and hydrogenated marine oil-containing diets.Biochim Biophys Acta. 1979 Jun 21;573(3):417-29 PMID: 465511
-
The rapid preparation of peroxisomes from rat liver by using a vertical rotor.Biochem J. 1979 May 15;180(2):445-8 PMID: 486122
Contact
No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong
Qilu Normal University · Genelibs Bioinformatics Lab
750 Shunhua Rd, Jinan
2F, Bldg F, University Science Park
Tel: 0531-88819269
WeChat Official Account
Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.
Business Email
E-mail: [email protected]
Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2
