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PMID: 7370020 Published · ppublish English Journal Article

Contribution of rat liver and gastrointestinal tract to whole-body protein synthesis in the rat.

The Biochemical journal ·Vol. 186 ·No. 1 ·1980-01-15 ·Pages 381-3

McNurlan MA, Garlick PJ

Abstract

The rate of protein synthesis was assessed in liver, stomach, small and large intestine and in the whole body of rats by injection of 100 mumol of [14C]leucine/100 g body wt. In each of the tissues turnover was very rapid, so that taken together they accounted for 43% of the protein synthesized by the whole animal.

MeSH Terms
Animals Digestive System/metabolism Kinetics Leucine/metabolism Liver/metabolism Methods Protein Biosynthesis Rats
Chemicals
Leucine
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
McNurlan M A
Garlick P J
References (4)
4 references, click to expand
  1. Compartmentation of free valine and its relation to protein turnover in perfused rat liver.
    J Biol Chem. 1972 May 10;247(9):2776-84 PMID: 5025099
  2. The effect of protein deprivation and starvation on the rate of protein synthesis in tissues of the rat.
    Biochim Biophys Acta. 1975 Nov 18;414(1):71-84 PMID: 811266
  3. Cereals as protein sources.
    Proc Nutr Soc. 1977 Sep;36(2):137-42 PMID: 333461
  4. The effect of starvation on the rate of protein synthesis in rat liver and small intestine.
    Biochem J. 1979 Feb 15;178(2):373-9 PMID: 444219
Article Info
Journal
The Biochemical journal
Abbr.
Biochem J
ISSN
0264-6021
Published
1980-01-15
Pages
381-3
Language
English
Region
England
NLM ID
2984726R
PMCID
PMC1161542
Subset
IM
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