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PMID: 73796 Published · ppublish English Clinical Trial Journal Article Randomized Controlled Trial

Unabsorbable carbohydrates and diabetes: Decreased post-prandial hyperglycaemia.

Lancet (London, England) ·Vol. 2 ·No. 7978 ·1976-07-24 ·Pages 172-4

Jenkins DJ, Goff DV, Leeds AR, Alberti KG, Wolever TM, Gassull MA, Hockaday TD

Abstract

Two test meals were taken in random order on separate days by 8 non-insulin-requiring diabetic volunteers after 14-hour overnight fasts. Addition of 16 g guar and 10 g pectin to the control meal containing 106 g carbohydrate decreased markedly and significantly the rise in blood-glucose between 30 and 90 minutes and also resulted in significantly lower insulin levels between 30 and 120 minutes. When these meals were fed to 3 insulin-dependent diabetic subjects, a similar flattening of the post-prandial glucose rise ensued. This addition of certain forms of dietary fibre to the diet of diabetics significantly decreases post-prandial hyperglycaemia and would be expected to improve the control of blood-glucose concentration.

MeSH Terms
Blood Glucose/analysis Cellulose/therapeutic use Diabetes Mellitus/diet therapy,metabolism Dietary Carbohydrates/metabolism,therapeutic use Dietary Fiber/metabolism,therapeutic use Eating Female Humans Insulin/blood Intestinal Absorption Male Mannans/therapeutic use Middle Aged Pectins/therapeutic use Polysaccharides/therapeutic use Time Factors
Chemicals
Blood Glucose Dietary Carbohydrates Dietary Fiber Insulin Mannans Polysaccharides Pectins Cellulose
Authors & Affiliations
7 authors, click to expand affiliations / ORCID
Jenkins D J
Goff D V
Leeds A R
Alberti K G
Wolever T M
Gassull M A
Hockaday T D
Article Info
Journal
Lancet (London, England)
Abbr.
Lancet
ISSN
0140-6736
Published
1976-07-24
Pages
172-4
Language
English
Region
England
NLM ID
2985213R
Subset
IM
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