2,3,7,8,-Tetrachlorodibenzo-p-dioxin: segregation of toxocity with the Ah locus.

Animals Aryl Hydrocarbon Hydroxylases/metabolism Atrophy/chemically induced Chromosome Mapping Cleft Palate/chemically induced Cytosol/metabolism Dioxins/toxicity Dose-Response Relationship, Drug Enzyme Induction Female In Vitro Techniques Mice Mice, Inbred Strains Mutagens Polychlorinated Dibenzodioxins/administration & dosage,metabolism,toxicity Protein Binding Receptors, Drug/genetics Structure-Activity Relationship Thymus Gland/pathology

Dioxins Mutagens Polychlorinated Dibenzodioxins Receptors, Drug Aryl Hydrocarbon Hydroxylases