A mutant of CHO-K1 cells deficient in two nonsequential steps of de novo purine biosynthesis.

Amidophosphoribosyltransferase/genetics Ammonia/metabolism Animals Carbon-Nitrogen Ligases with Glutamine as Amide-N-Donor Cell-Free System Cricetinae Genetic Complementation Test Glutamine/metabolism Glycine/analogs & derivatives,genetics Ligases/genetics Mutation Pentosyltransferases/genetics Phenotype Purines/biosynthesis Ribonucleotides/genetics

Purines Ribonucleotides Glutamine Ammonia Pentosyltransferases Amidophosphoribosyltransferase Ligases Carbon-Nitrogen Ligases with Glutamine as Amide-N-Donor phosphoribosylformylglycinamidine synthetase Glycine