Recognition of specific DNA sequences in eukaryotic chromosomes.
The packaging of DNA into chromatin probably places certain restrictions on how specific DNA sequences can be recognized by DNA sequence specific recognition proteins (SRP). Several unique features of this type of interaction are discussed. Specifically, as a consequence of the coiling of the DNA about a histone core, it is proposed that DNA recognition sites will be compound and that each element of the compound recognition site will be about 10 - 20 b.p. in length and distributed at approximately 80 b.p. intervals--the periodicity of the DNA wrapping around the nucleosome.
19 references, click to expand
-
Solenoidal model for superstructure in chromatin.Proc Natl Acad Sci U S A. 1976 Jun;73(6):1897-901 PMID: 1064861
-
Structure of nucleosome core particles of chromatin.Nature. 1977 Sep 1;269(5623):29-36 PMID: 895884
-
Higher order coiling of DNA in chromatin.Cell. 1977 Sep;12(1):83-100 PMID: 409504
-
On the occurrence of nucleosome phasing in chromatin.Cell. 1977 Nov;12(3):829-36 PMID: 336221
-
Why genes in pieces?Nature. 1978 Feb 9;271(5645):501 PMID: 622185
-
Nucleosomal DNA is digested to repeats of 10 bases by exonuclease III.Cell. 1978 Feb;13(2):281-93 PMID: 627037
-
Subunit structure of chromatin and the organization of eukaryotic highly repetitive DNA: indications of a phase relation between restriction sites and chromatin subunits in African green monkey and calf nuclei.J Mol Biol. 1977 Dec 15;117(3):657-77 PMID: 416220
-
Nucleosome arcs and helices.Science. 1978 Oct 20;202(4365):280-6 PMID: 694532
-
Sites in simian virus 40 chromatin which are preferentially cleaved by endonucleases.Cell. 1978 Dec;15(4):1511-8 PMID: 215331
-
Origin of DNA replication in papovavirus chromatin is recognized by endogenous endonuclease.Proc Natl Acad Sci U S A. 1978 Dec;75(12):5964-8 PMID: 216004
-
A stretch of "late" SV40 viral DNA about 400 bp long which includes the origin of replication is specifically exposed in SV40 minichromosomes.Cell. 1979 Feb;16(2):453-66 PMID: 222461
-
The chromatin structure of specific genes: I. Evidence for higher order domains of defined DNA sequence.Cell. 1979 Apr;16(4):797-806 PMID: 455449
-
Higher-order structures of chromatin in solution.Eur J Biochem. 1979 Jul;97(2):593-602 PMID: 467433
-
Involvement of histone H1 in the organization of the nucleosome and of the salt-dependent superstructures of chromatin.J Cell Biol. 1979 Nov;83(2 Pt 1):403-27 PMID: 387806
-
A phase relationship associates tRNA structural gene sequences with nucleosome cores.Cell. 1979 Dec;18(4):1173-83 PMID: 519765
-
DNA methylation: correlation with DNase I sensitivity of chicken ovalbumin and conalbumin chromatin.Nucleic Acids Res. 1979 Dec 20;7(8):2105-13 PMID: 523315
-
Organization of spacer DNA in chromatin.Proc Natl Acad Sci U S A. 1979 Dec;76(12):6326-30 PMID: 392519
-
Tissue-specific DNA cleavages in the globin chromatin domain introduced by DNAase I.Cell. 1980 Jun;20(2):451-60 PMID: 7388947
-
Nucleosome structure.Annu Rev Biochem. 1980;49:1115-56 PMID: 6996562
Contact
No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong
Qilu Normal University · Genelibs Bioinformatics Lab
750 Shunhua Rd, Jinan
2F, Bldg F, University Science Park
Tel: 0531-88819269
WeChat Official Account
Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.
Business Email
E-mail: [email protected]
Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2
