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PMID: 7462235 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Evidence for different hepatic microsomal monooxygenases catalyzing omega- and (omega-1)-hydroxylations of prostaglandins E1 and E2. Effects of inducers of monooxygenase on the kinetic constants of prostaglandin hydroxylation.

The Journal of biological chemistry ·Vol. 256 ·No. 5 ·1981-03-10 ·Pages 2168-75

Theoharides AD, Kupfer D

Abstract

暂无摘要

MeSH Terms

Animals Chromatography, High Pressure Liquid Cytochrome P-450 Enzyme System/metabolism Gas Chromatography-Mass Spectrometry Kinetics Linoleic Acids/pharmacology Lipid Peroxides/pharmacology Male Microsomes, Liver/drug effects,enzymology Mixed Function Oxygenases/metabolism Phenobarbital/pharmacology Prostaglandins E Rabbits Substrate Specificity

Chemicals

Linoleic Acids Lipid Peroxides Prostaglandins E linoleic acid hydroperoxide Cytochrome P-450 Enzyme System Mixed Function Oxygenases prostaglandin omega hydroxylases Phenobarbital

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Theoharides A D

Kupfer D

Article Info

Journal

The Journal of biological chemistry

Abbr.

J Biol Chem

ISSN

0021-9258

Published

1981-03-10

Pages

2168-75

Language

English

Region

United States

NLM ID

2985121R

Subset

Grants

NIGMS NIH HHS · GM 22688 · United States

NCRR NIH HHS · RR 00317 · United States

External Links

PubMed source View journal details

Analysis Services

Evidence for different hepatic microsomal monooxygenases catalyzing omega- and (omega-1)-hydroxylations of prostaglandins E1 and E2. Effects of inducers of monooxygenase on the kinetic constants of prostaglandin hydroxylation.

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