Control of vascular permeability by polymorphonuclear leukocytes in inflammation.

Nature ·Vol. 289 ·No. 5799 ·1981-02-19 ·Pages 646-50

Wedmore CV, Williams TJ

Abstract

Polymorphonuclear leukocytes infiltrate tissues in response to an inflammatory stimulus to remove invading microorganisms and cell debris. We present eivdence that these scaveging cells have another, more sophisticated role in that they are involved in the control of fluid efflux through the blood vessel wall which leads to tissue oedema.

MeSH Terms

Animals Capillary Permeability Chemotaxis, Leukocyte Complement System Proteins/physiology Endothelium/physiopathology Inflammation/physiopathology Neutrophils/physiology Prostaglandins/physiology Rabbits

Chemicals

Prostaglandins Complement System Proteins

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Wedmore C V

Williams T J

Article Info

Journal

Nature

Abbr.

Nature

ISSN

0028-0836

DOI

10.1038/289646a0

Published

1981-02-19

Pages

646-50

Language

English

Region

England

NLM ID

0410462

Subset

External Links

PubMed source DOI: 10.1038/289646a0 View journal details

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Control of vascular permeability by polymorphonuclear leukocytes in inflammation.

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