Plasmalemmal caveolae and GPI-anchored membrane proteins.

Current opinion in cell biology ·Vol. 5 ·No. 4 ·1993-08-00 ·Pages 647-52

Anderson RG

Abstract

Caveolae are essential endocytic organelles that use glycosyl-phosphatidyl-inositol (GPI)-anchored membrane proteins to concentrate low molecular weight substances before delivery to the cell. Caveolae and GPI-anchored proteins are uniquely adapted for this task. Recent advances suggest that this endocytic pathway also has an important role in modulating the interaction of a cell with its environment. Many vital functions that occur in this organelle remain to be discovered.

MeSH Terms

Animals CSK Tyrosine-Protein Kinase Calcium Channels/analysis Cell Membrane/ultrastructure Glycosylphosphatidylinositols/chemistry Humans Inositol 1,4,5-Trisphosphate Inositol 1,4,5-Trisphosphate Receptors Membrane Proteins/chemistry Organelles/ultrastructure Protein-Tyrosine Kinases/chemistry Proto-Oncogene Proteins pp60(c-src)/chemistry Receptors, Cytoplasmic and Nuclear/analysis src-Family Kinases

Chemicals

Calcium Channels Glycosylphosphatidylinositols ITPR1 protein, human Inositol 1,4,5-Trisphosphate Receptors Membrane Proteins Receptors, Cytoplasmic and Nuclear Inositol 1,4,5-Trisphosphate Protein-Tyrosine Kinases CSK Tyrosine-Protein Kinase Proto-Oncogene Proteins pp60(c-src) src-Family Kinases CSK protein, human

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Anderson R G

Department of Cell Biology and Neuroscience, University of Texas, Southwestern Medical Center, Dallas 75235.

Article Info

Journal

Current opinion in cell biology

Abbr.

Curr Opin Cell Biol

ISSN

0955-0674

DOI

10.1016/0955-0674(93)90135-d

Published

1993-08-00

Pages

647-52

Language

English

Region

England

NLM ID

8913428

Subset

External Links

PubMed source DOI: 10.1016/0955-0674(93)90135-d View journal details

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Plasmalemmal caveolae and GPI-anchored membrane proteins.

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