Adenovirus-mediated gene transfer for cystic fibrosis: Part A. Safety of dose and repeat administration in the nasal epithelium. Part B. Clinical efficacy in the maxillary sinus.

Human gene therapy ·Vol. 6 ·No. 2 ·1995-02-00 ·Pages 205-18

Welsh MJ, Zabner J, Graham SM, Smith AE, Moscicki R, Wadsworth S

Abstract

暂无摘要

MeSH Terms

Adenoviruses, Human/genetics Clinical Protocols Clinical Trials as Topic Cystic Fibrosis/therapy Cystic Fibrosis Transmembrane Conductance Regulator Female Gene Transfer Techniques/adverse effects Genetic Therapy/adverse effects Genetic Vectors/genetics Humans Male Maxillary Sinus Membrane Proteins/administration & dosage,genetics,therapeutic use Nasal Mucosa

Chemicals

CFTR protein, human Membrane Proteins Cystic Fibrosis Transmembrane Conductance Regulator

Authors & Affiliations

6 authors, click to expand affiliations / ORCID

Welsh M J

Howard Hughes Medical Institute, Department of Internal Medicine, University of Iowa College of Medicine, Iowa City 52242, USA.

Zabner J

Graham S M

Smith A E

Moscicki R

Wadsworth S

Article Info

Journal

Human gene therapy

Abbr.

Hum Gene Ther

ISSN

1043-0342

DOI

10.1089/hum.1995.6.2-205

Published

1995-02-00

Pages

205-18

Language

English

Region

United States

NLM ID

9008950

Subset

External Links

PubMed source DOI: 10.1089/hum.1995.6.2-205 View journal details

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Adenovirus-mediated gene transfer for cystic fibrosis: Part A. Safety of dose and repeat administration in the nasal epithelium. Part B. Clinical efficacy in the maxillary sinus.

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